Evaluation of the Effect of Oxidative Stress Generated by Cadmium (Cd) in the Yeast Saccharomyces cerevisiae

Inhibition of the mitochondrial electron transfer chain and induction of reactive oxygen species (ROS) production are one of the roots of cadmium (Cd) toxicity. Our work concerns the study of the effects of a heavy metal; Cadmium (Cd) on the biochemical parameters, of microorganism bioaccumulator and bioindicators of pollution Saccharomyces cerevisiae. The main results show that the presence of Cadmium affects the growth of yeast, and biochemical assays reveal an increase significant of total protein and a decrease in the rate of carbohydrates. With respect to biomarkers, we note a significant decrease in the level of GSH. The results of this study demonstrate a metabolic imbalance associated oxidative stress in Saccharomyces cerevisiae.